The IronTract challenge: Validation and optimal tractography methods for the HCP diffusion acquisition scheme

12/08/2020: 14:30  - 15:15 
Room: Wednesday Parallel 4 
We present results from IronTract, the first challenge to evaluate tractography on the two-shell diffusion scheme of the Human Connectome Project (HCP). Accuracy was evaluated by comparison to tracer injections in the same macaque brains as the diffusion data. Training and validation datasets involved different injection sites. We observed that optimizing data analysis with respect to one injection site does not guarantee optimality for another; encouragingly, two teams could achieve consistently high performance in both datasets. We also found that, when analysis methods are optimized, the HCP scheme may achieve similar accuracy as a more demanding diffusion spectrum imaging acquisition.

Author String

Chiara Maffei, Gabriel Girard, Kurt Schilling, Nagesh Adluru, Dogu Aydogan, Andac Hamamci, Fang-Cheng Yeh, Matteo Mancini, Ye Wu, Alessia Sarica, Achille Teillac, Steven Baete, Davood Karimi, Ying-Chia Lin, Fernando Boada, Nathalie Richard, Bassem Hiba, Aldo Quattrone, Yoonmi Hong, Dinggang Shen, Pew-Thian Yap, Tommy Boshkovski, Jennifer S. W. Campbell, Nikola Stikov, G. Bruce Pike, Barbara B. Bendlin, Andrew L. Alexander, Vivek Prabhakaran, Adam Anderson, Bennett A. Landman, Erick J.Z. Canales-Rodrígue, Muhamed Barakovic, Jonathan Rafael-Patino, Thomas Yu, Gaëtan Rensonnet, Simona Schiavi, Alessandro Daducci, Marco Pizzolato, Elda Fischi-Gomez, Jean-Philippe Thiran, George Dai, Giorgia Grisot, Nikola Lazovski, Albert Puente, Matt Rowe, Irina Sanchez, Vesna Prchkovska, Robert Jones, Julia Lehman, Suzanne Haber, Anastasia Yendiki 

Institution String

Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Signal Processing Lab (LTS5), École Polytechnique Fédérale de Lausanne, Institute of Imaging Science, Vanderbilt University, University of Wisconsin, Department of Neuroscience and Biomedical Engineering, Aalto University, Department of Biomedical Engineering, Faculty of Engineering, Yeditepe University, Department of Neurological Surgery, University of Pittsburgh, Department of Neuroscience, Brighton and Sussex Medical School, University of Sussex, NeuroPoly Lab, Polytechnique Montreal, Department of Radiology and BRIC, University of North Carolina, Neuroscience Research Center, University Magna Graecia of Catanzaro, CNRS/ISC, Université de Bordeaux, CNRS/INCIA, Center for Advanced Imaging Innovation and Research (CAI2 R), NYU School of Medicine, Center for Biomedical Imaging, Dept. of Radiology, NYU School 


Chiara Maffei, Massachusetts General Hospital and Harvard Medical School