In-vivo laminar CBF fMRI using high-resolution pseudo-continuous arterial spin labeling at 7T

13/08/2020: 15:05  - 15:50 
1232 
Oral 
Room: Thursday Parallel 4 
In-vivo laminar CBF fMRI was performed
by high resolution (0.5×0.5×1.5 mm3) inner-volume GRASE with optimized pCASL labeling at 7T.
Activation of finger-tapping task (5 blocks, TA=10 min) was reliably detected in
all 4 subjects.
Both rest/FT CBF peaks in the middle layers,
which corresponds to highest capillary density in cortex layer IV.
FT evoked CBF increase shows one peak in middle
layer, and a second shoulder in deep layer. The
capability to provide quantitative CBF measurements at both baseline and task
activation with high specificity to neuronal activities is a unique strength of
ASL fMRI compared to other fMRI techniques.

Author String

Xingfeng Shao, Kay Jann, Kai Wang, Fanhua Guo, Peng Zhang, Danny JJ Wang 

Institution String

University of Southern California, University of Southern California, University of Southern California, University of Southern California, Chinese Academy of Sciences, Chinese Academy of Sciences, University of Southern California, University of Southern California 

Speaker

Xingfeng Shao, University of Southern California