Mapping ocular dominance columns in humans using GE-EPI, SE-EPI and SS-SI-VASO at 7 T

13/08/2020: 15:05  - 15:50 
1230 
Oral 
Room: Thursday Parallel 4 
Functional
MRI studies classically rely on the use of GE-EPI sequences. However,
the GE-based signal is inherently sensitive to large veins,
which
impairs its use in high-resolution fMRI application. Other BOLD-
and CBV-based approaches like SE-EPI and SS-SI-VASO, respectively,
promise
a higher specificity at the expense of sensitivity.
In the present work, we tested if ocular dominance columns (ODCs) can
be detected using GE-EPI, SE-EPI and SS-SI-VASO at 7 T.
ODCs
could be reliably
mapped
using all three acquisition methods. Furthermore, we
could show for the first time ODCs
in
humans by exploiting
the functional CBV response
using SS-SI-VASO.

Author String

Daniel Haenelt, Nikolaus Weiskopf, Lenka Vaculciakova, Roland Mueller, Shahin Nasr, Jonathan Polimeni, Roger Tootell, Laurentius Huber, Martin Sereno, Robert Trampel 

Institution String

Max Planck Institute for Human Cognitive and Brain Sciences, International Max Planck Research School on Neuroscience of Communication: Function, Structure, and Plasticity, Max Planck Institute for Human Cognitive and Brain Sciences, Max Planck Institute for Human Cognitive and Brain Sciences, International Max Planck Research School on Neuroscience of Communication: Function, Structure, and Plasticity, Max Planck Institute for Human Cognitive and Brain Sciences, Athinoula A. Martinos Center for Biomedical Imaging, Harvard Medical School, Athinoula A. Martinos Center for Biomedical Imaging, Harvard Medical School, Athinoula A. Martinos Center for Biomedical Imaging, Harvard Medical School, Maastricht Brain Imaging Center, San Diego State University, Max Planck Institute for Human Cognitive and Brain Sciences 

Speaker

Daniel Haenelt, Max Planck Institute for Human Cognitive and Brain Sciences