Sub-Millimeter Spiral fMRI Combining Magnitude and Phase BOLD Contrast

13/08/2020: 15:05  - 15:50 
1227 
Oral 
Room: Thursday Parallel 4 


We investigate the spatial specificity of sub-millimeter
(0.8mm) single-shot spiral fMRI, and its feasibility for functional phase
contrast. Scrutinizing activation patterns of a visual paradigm in 6 subjects, we
find that significant contrast changes occur between adjacent voxels, contributing
to the evidence of spatial specificity of spiral acquisition as well as gradient
echo BOLD contrast, and its possible applications in laminar or columnar fMRI.
Furthermore, the vessel-localized nature of the phase activation suggests its suitability for masking macrovascular confound effects.

Author String

Lars Kasper, Maria Engel, Jakob Heinzle, Matthias Mueller-Schrader, Jonas Reber, Thomas Schmid, Christoph Barmet, Bertram Wilm, Klaas Stephan, Klaas Pruessmann 

Institution String

Institute for Biomedical Engineering, ETH Zurich and University of Zurich, Institute for Biomedical Engineering, ETH Zurich and University of Zurich, Translational Neuromodeling Unit, Institute for Biomedical Engineering, University of Zurich and ETH Zurich, Translational Neuromodeling Unit, Institute for Biomedical Engineering, University of Zurich and ETH Zurich, Institute for Biomedical Engineering, ETH Zurich and University of Zurich, Institute for Biomedical Engineering, ETH Zurich and University of Zurich, Institute for Biomedical Engineering, ETH Zurich and University of Zurich, Institute for Biomedical Engineering, ETH Zurich and University of Zurich, Translational Neuromodeling Unit, Institute for Biomedical Engineering, University of Zurich and ETH Zurich, Wellcome Trust Centre for Neuroimaging, University College London, Max Planck Institute for Metabolism Research, Institute for Biomedical Engineering, ETH Zurich and University of Zurich 

Speaker

Lars Kasper, Techna Institute, University Health Network, Toronto, Canada