Apparent attenuation of BOLD macro-vascular contributions with high-frequency stimuli

Program No:

3826 

Poster Type:

Digital Poster 

Authors:

Daniel Gomez, Nina Fultz, Shahin Nasr, Jonathan Polimeni, Laura Lewis

Institutions:

Massachusetts General Hospital, Harvard Medical School, Boston University, Massachusetts General Hospital, Boston University, Massachusetts General Hospital, Harvard Medical School, Massachusetts General Hospital, Harvard Medical School, Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, Massachusetts General Hospital, Boston University

Digital Poster Presenter:

Daniel E. Gomez  
Massachusetts General Hospital

Synopsis:

Fast fMRI signals may reflect an enhanced relative contribution of fast microvascular signals in the BOLD response. In the current work we tested whether using fast oscillatory stimulus frequencies indeed leads to a relative attenuation of the signal from draining veins, as compared to the microvasculature. Our results suggest that the relative contribution of deep BOLD signals is enhanced at high stimulus frequencies.

1100 fMRI:

fMRI Contrast Mechanisms

Additional Category:

fMRI: Contrast & Physiology