Functional line-scanning in humans with ultra-high spatiotemporal resolution: reconstruction and BOLD sensitivity assessment

Program No:

3876 

Poster Type:

Digital Poster 

Authors:

Luisa Raimondo, Tomas Knapen, ─║caro Oliveira, Xin Yu, Serge Dumoulin, Wietske van der Zwaag, Jeroen Siero

Institutions:

Spinoza Centre for Neuroimaging, Spinoza Centre for Neuroimaging, VU University, Spinoza Centre for Neuroimaging, Max Planck Institute for Biological Cybernetics, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Spinoza Centre for Neuroimaging, VU University, Spinoza Centre for Neuroimaging, University Medical Centre Utrecht, Spinoza Centre for Neuroimaging

Digital Poster Presenter:

Luisa Raimondo  
Spinoza Centre for Neuroimaging

Synopsis:

We present
initial results of line-scanning fMRI in humans. The potential of this
technique lies in the combination of both high spatial and temporal resolution
while sacrificing spatial coverage outside the region of interest. We reached a
250 μm resolution along the line direction with a temporal resolution of 200
ms. Coil sensitivity profiles and the average tSNR per channel were used to optimize the line reconstructions. We obtained
similar BOLD sensitivity compared to standard 2D GE-EPI BOLD and high spatial
specificity for a visual task. Hence, we demonstrate the feasibility of
ultra-high spatiotemporal resolution in humans using line-scanning.

1100 fMRI:

fMRI Acquisition 1

Additional Category:

fMRI: Acquisition & Applications